Preparing for Your VYJUVEK Treatment
Cleansing & Bathing
Bathing considerations before applying VYJUVEK
During the clinical studies, patients did not bathe prior to VYJUVEK application, so remember, bathing first is not a requirement. Choose what works best for you. Patients have shared that it often works well for their schedule to apply VYJUVEK after a bath or shower. Here’s what’s important to keep in mind:
- Before applying VYJUVEK, the wound area(s) you are treating should be free of medicines, ointments, drainage, scabbing, and dead skin as much as possible, without causing additional wound damage
- Before applying VYJUVEK, it may be helpful to use saline wipes or rinses to clean wound area(s)
Salt or Epsom Salt
Adults: Add 2 pounds of salt to 40 gallons of tub water or a half‑filled bathtub.
Babies and Infants: Add 5 teaspoons of salt to each gallon of bath water.
Saltwater or epsom salt baths do not impact how VYJUVEK works and can be taken prior to application without the need for rinsing.
Keep in mind: Using bleach and vinegar before VYJUVEK application can reduce how well
VYJUVEK works.
If you aren’t able to avoid using bleach and vinegar 24 hours before application, make sure you rinse thoroughly with saline or plain water to remove these products from your wound prior to application.
Bleach
Diluted bleach in bathwater can be beneficial in improving the skin barrier and reducing itching.
Small amounts of bleach (1/2 cup in a 40-gallon bathtub of water, or 1 teaspoon in a gallon of water for localized soaks or compresses) do not affect how VYJUVEK works if you rinse after bathing.
Vinegar
Acetic acid solutions (2 gallons of 5% acetic acid white vinegar for a 40-gallon bathtub) can help to reduce Pseudomonas, a frequent colonizer of DEB wounds.
Vinegar solutions at this concentration do not affect how VYJUVEK works if you rinse after bathing.
Treatment Preparation
How to prepare for treatment
24 Hours Before Application
Twenty-four hours before applying VYJUVEK, do not use any of the products listed below or any products that contain these ingredients:
- Bactroban
- Calmoseptine®
- Chlorhexidine
- Hibiclens®
- Honey
- Hydrogen peroxide
- Mupirocin
- Octenisept®
- Silver
- Tea tree oil
- Topical CBD
- Vanicream
- Vashe
- Vinegar
- Zinc (in concentrations >12.8%)
Herbal remedies and other topical ointments should be discussed with your doctor prior to treating your wounds with VYJUVEK.
If you can’t avoid the above items in the 24 hours before VYJUVEK application, ensure you rinse the wound area well with clean water or saline prior to applying.
You may return to using these items after the first dressing change following VYJUVEK application.
SHIPMENT
What will be sent to me?
When you receive your first shipment of VYJUVEK from Option Care Health®, you will also receive the other supplies needed to start treatment.
You can request Vaseline® gauze or Xeroform® from Option Care Health® pharmacy as another option for your hydrophobic dressing. Your PAL can help you explore other dressing alternatives.
Syringes containing VYJUVEK
Scissors
Plastic WrapYou can request Vaseline® gauze or Xeroform® from Option Care Health
Protective gloves
Sealable plastic bags
70% isopropyl alcohol spray
(to disinfect used bandages, not for use on wounds)
Sharps container
Option Care Health pharmacy will provide all of these supplies as a part of your ongoing shipments of VYJUVEK.
Your Patient Access Liaison is always available to answer questions related to getting
ready for treatment. Call 1‑844‑5‑KRYSTAL.
Learn about the many options for hydrophobic dressings, so you can decide what works best for the wound area(s) where you are applying VYJUVEK:
INDICATION AND USAGE
VYJUVEK is a topical gel used to treat wounds in adult and pediatric patients (from birth) with dystrophic epidermolysis bullosa (DEB).
IMPORTANT SAFETY INFORMATION
VYJUVEK gel should be applied by a healthcare professional, patient, or caregiver.
After treatment, patients and caregivers should be careful not to touch treated wounds and dressings until the next bandage change. If accidentally exposed to the VYJUVEK gel, clean the affected area.
Wash hands and wear protective gloves when changing wound dressings. Disinfect bandages from the first dressing change with a virucidal agent and dispose of the disinfected bandages in a separate sealed plastic bag in household waste. Dispose of the subsequent used dressings in a sealed plastic bag in household waste.
The most common adverse reactions (>5%) were itching, chills, redness, rash, cough, and runny nose. These are not all the possible side effects with VYJUVEK. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or to the Sponsor at 1-844-557-9782.
Please see Important Safety Information above and click here for full Prescribing Information.
IMPORTANT SAFETY INFORMATION
INDICATION AND USAGE
VYJUVEK is a topical gel used to treat wounds in adult and pediatric patients (from birth) with dystrophic epidermolysis bullosa (DEB).
IMPORTANT SAFETY INFORMATION
VYJUVEK gel should be applied by a healthcare professional, patient, or caregiver.
After treatment, patients and caregivers should be careful not to touch treated wounds and dressings until the next bandage change. If accidentally exposed to the VYJUVEK gel, clean the affected area.
Wash hands and wear protective gloves when changing wound dressings. Disinfect bandages from the first dressing change with a virucidal agent and dispose of the disinfected bandages in a separate sealed plastic bag in household waste. Dispose of the subsequent used dressings in a sealed plastic bag in household waste.
The most common adverse reactions (>5%) were itching, chills, redness, rash, cough, and runny nose. These are not all the possible side effects with VYJUVEK. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or to the Sponsor at 1-844-557-9782.
Please see Important Safety Information above and click here for full Prescribing Information.
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