FOR US RESIDENTS ONLY
NOW APPROVED For the treatment of Dystrophic Epidermolysis Bullosa (DEB) in patients 6 months and older
Support & Resources

About Krystal Connect

ABOUT KRYSTAL CONNECT

Krystal Connect is a personalized patient support program to help you throughout your treatment journey

Whether you’re considering treatment, ready to start, or looking for more information about dystrophic epidermolysis bullosa (DEB), Krystal Connect is here to help you.

When you contact and enroll in Krystal Connect, you will be connected to a dedicated team, including your Patient Access Liaison (PAL) and Care Coordinator*. Your team is available to:

  • Provide education about VYJUVEK and DEB
  • Help you navigate the insurance process
  • Inform you about financial assistance programs. For eligible patients, Krystal Connect may be able to reduce out-of-pocket costs or help locate assistance options. Eligible patients may pay as little as $0 for VYJUVEK.
  • Support treatment planning and administration. In preparation for your first appointment, your PAL will be in touch to make sure you have all the information you need and know what to expect
  • Provide information to help you locate a treating doctor in your area


*PALs and care coordinators do not direct patient care or provide medical advice.

Krystal Connect™ logo
Call Krystal Connect at 1-844-5-KRYSTAL

VYJUVEK can be administered at a healthcare setting or at your home, depending on your doctor's instructions, your insurance plan coverage, and your preference.

VYJUVEK House icon

If you and your doctor decide you will receive VYJUVEK in your home, your Krystal Connect Patient Access Liaison (PAL) will introduce you to the services offered by Option Care Health®, a national in-home nursing and pharmacy service. Together, your PAL and Option Care Health team will ensure you have everything needed for in-home administration. They will coordinate the weekly shipping of VYJUVEK to your home and weekly nurse visit to administer it.

VYJUVEK office icon

If you and your doctor decide you will receive VYJUVEK in a healthcare setting, Krystal Connect will work with your healthcare office to schedule your weekly VYJUVEK delivery to the office. You will then work directly with the office to schedule your weekly appointments.

GETTING STARTED

The steps to obtaining VYJUVEK treatment

If you and your doctor decide that VYJUVEK is an option for you, you’ll follow the steps below:

Enrollment form

1. Enrollment:
After determining VYJUVEK is right for you, you and your doctor will complete the VYJUVEK Enrollment Form. This will serve as your prescription, and allows Krystal Connect to begin working with you.
Download the Enrollment Form

Welcome call

2. Welcome call:
Once Krystal Connect receives your enrollment form, your PAL will reach out to welcome you, to learn more about your needs, and to explain how they can help.

Evaluating coverage options

3. Helping evaluate your coverage options:
Your PAL will help with benefits investigation to better understand your insurance coverage and next steps. If appropriate, your PAL may share information and resources about additional financial assistance options. These may include:

  • For eligible commercially insured patients, our $0 Copay Program can help reduce out-of-pocket costs to as low as $0*
  • For eligible patients without insurance coverage, or who may have insurance but don’t have VYJUVEK coverage, our Patient Assistance Program (PAP) may be able to provide VYJUVEK at no cost

Determining treatment location

4. Determining your treatment location, and starting treatment:
VYJUVEK can be administered by a healthcare professional at a healthcare professional setting (for example, a clinic) or home setting, depending on your doctor’s instructions, your insurance plan coverage, and your preference.
Your Krystal Connect team will work with you and your doctor to confirm the location for VYJUVEK treatment, confirm your appointment, and help coordinate VYJUVEK delivery.

Ongoing support

5. Ongoing support:
VYJUVEK is administered weekly by a healthcare professional and should be applied weekly to wounds until they are closed.
Your Krystal Connect team will check in with you from time to time. They can help answer new questions or, should your needs or situation change, help you to avoid interruption to your treatment.

To have this information handy, download the Krystal Connect brochure. Download the Brochure

*Patient Eligibility & Terms and Conditions: The VYJUVEK Copay Program is available only to commercially insured patients with a valid prescription for VYJUVEK. Patients must be US citizens or residents for at least six months. Patients or their guardian must be 18 years of age or older to enroll in the program. Patients are not eligible for copay assistance through the VYJUVEK Copay Program if they are cash-paying patients, or enrolled in any state or federally funded programs for which drug prescriptions or coverage could be paid in part or in full, including, but not limited to, Medicare Part B, Medicare Part D, Medicaid, Medigap, VA, DoD, or TRICARE (collectively, “Government Programs”), or where prohibited by law. This offer is not health insurance. The VYJUVEK Copay Program applies only to out of pocket costs associated with VYJUVEK and not the cost of related medical services. In any calendar year commencing January 1, the maximum copay benefit amount paid by Krystal Biotech, Inc. will be $15,000. Eligible patients may pay as little as $0 per prescription, up to the annual maximum copay assistance amount of $15,000. Additional terms and conditions apply. See www.krystalconnect.com/pdf/us_terms.pdf for full terms and conditions.

The VYJUVEK Patient Assistance Program (PAP) is designed to provide VYJUVEK at no cost to eligible patients who meet certain financial need and insurance coverage eligibility criteria. Patients may be eligible to receive free drug if they demonstrate qualifying financial need, are uninsured or functionally uninsured, are US citizens or residents for at least six months, and have a valid prescription for VYJUVEK as supported by information provided in the program application. Eligibility does not guarantee approval for participation In the program. The PAP does not cover the cost of previously purchased product or medical services. See www.krystalconnect.com/pdf/us_terms.pdf for full terms and conditions.

INDICATION AND USAGE

VYJUVEK is a topical gel used to treat wounds in patients 6 months and older with dystrophic epidermolysis bullosa (DEB).

IMPORTANT SAFETY INFORMATION

VYJUVEK gel must be applied by a healthcare provider.

After treatment, patients and caregivers should be careful not to touch treated wounds and dressings for 24 hours. If accidentally exposed to the VYJUVEK gel, clean the affected area.

Wash hands and wear protective gloves when changing wound dressings. Disinfect bandages from the first dressing change with a virucidal agent, and dispose of the disinfected bandages in a separate sealed plastic bag in household waste. Dispose of the subsequent used dressings in a sealed plastic bag in household waste.

Patients should avoid touching or scratching wound sites or wound dressings.

The most common adverse reactions (>5%) were itching, chills, redness, rash, cough, and runny nose. These are not all the possible side effects with VYJUVEK. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or to the Sponsor at 1-844-557-9782.

  • Please see Important Safety Information above and click here for full Prescribing Information.
IMPORTANT SAFETY INFORMATION
INDICATION AND USAGE

VYJUVEK is a topical gel used to treat wounds in patients 6 months and older with dystrophic epidermolysis bullosa (DEB).

IMPORTANT SAFETY INFORMATION

VYJUVEK gel must be applied by a healthcare provider.

After treatment, patients and caregivers should be careful not to touch treated wounds and dressings for 24 hours. If accidentally exposed to the VYJUVEK gel, clean the affected area.

Wash hands and wear protective gloves when changing wound dressings. Disinfect bandages from the first dressing change with a virucidal agent, and dispose of the disinfected bandages in a separate sealed plastic bag in household waste. Dispose of the subsequent used dressings in a sealed plastic bag in household waste.

Patients should avoid touching or scratching wound sites or wound dressings.

The most common adverse reactions (>5%) were itching, chills, redness, rash, cough, and runny nose. These are not all the possible side effects with VYJUVEK. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or to the Sponsor at 1-844-557-9782.

  • Please see Important Safety Information above and click here for full Prescribing Information.